Material Analysis · Structure & Spectroscopy

Circular Dichroism Spectroscopy (CD)

Characterise CD or CPL spectrum, ellipticity or luminescence dissymmetry factor, and secondary-structure or chiral-state changes using a scope agreed around your sample and decision.

  • CD or CPL spectrum
  • Ellipticity or luminescence dissymmetry…
  • Secondary-structure or chiral-state changes
  • Far-UV, near-UV, or visible CD
Representative Circular Dichroism Spectroscopy equipment selected for the TESTDOG service catalogue
Price
from£75
per sample, excl. VAT
Turnaround
7 working days
Preparation and scope dependent
Available platforms
Jasco J-1700Applied Photophysics Chirascan Q100BRIGHTTIME Chirascan, JASCO810
Typical outputs
CD or CPL spectrumMolar ellipticity or dissymmetry factorOptional secondary-structure or temperature-series analysisProcessed spectra

Why this service

What CD can help you understand

Circular Dichroism Spectroscopy is selected when the project needs defensible information on CD or CPL spectrum, ellipticity or luminescence dissymmetry factor, or secondary-structure or chiral-state…

01

CD or CPL spectrum

far-UV, near-UV, or visible CD

02

Ellipticity or luminescence dissymmetry factor

CPL emission

03

Secondary-structure or chiral-state changes

temperature, kinetics, or titration series

Choose the scope

Start from the question, not the tool

The method, preparation route and reporting depth depend on what you need to decide.

Far-UV, near-UV, or visible CD

CD or CPL spectrum

Best used when
CD or CPL spectrum
Typical result
CD or CPL spectrum
Preparation note
State the substrate, nominal thickness and whether sectioning or mounting is permitted.

Common outputs

A result package matched to the decision you need to make

Fields, conditions, processing and file formats are confirmed before work begins.

StandardCD or CPL spectrum

CD or CPL spectrum reported with the agreed units, sample reference and measurement conditions.

StandardMolar ellipticity or dissymmetry factor

Molar ellipticity or dissymmetry factor supplied in a labelled format suitable for direct sample or condition comparison.

OptionalOptional secondary-structure or temperature-series analysis

Optional secondary-structure or temperature-series analysis provided with the processing basis and quality checks agreed during technical review.

OptionalProcessed spectra

Processed spectra included when selected in the confirmed reporting scope.

Example results

What CD results can look like

CD result: The plot shows circular dichroism spectra of the dimer mixture with 0.25 wt% ISO- 2 at 37.1 °C and 40.0
CD spectrum

The plot shows circular dichroism spectra of the dimer mixture with 0.25 wt% ISO- 2 at 37.1 °C and 40.0.

Research source · source · CC BY

Sample requirements

What to provide before work begins

Provide representative, clearly labelled samples and identify the decision, feature or comparison that matters.

Suitable sampleSubmission requirementPlanning note
Film / coatingProvide the coated substrate or a flat film with the test surface and coating side clearly marked.State the substrate, nominal thickness and whether sectioning or mounting is permitted.
Liquid / solutionProvide a sealed, compatible container labelled with composition, concentration and solvent.Declare volatility, corrosivity, suspended solids and any storage or temperature requirement.
Biological / soft materialProvide fixed, preserved or otherwise stabilised material in the agreed container and medium.Declare biological hazards and confirm fixation, dehydration, temperature and disposal requirements.

Objective: state the decision, comparison or acceptance criterion the work must support.

Handling and access: declare hazards, instability, confidentiality, file constraints or special logistics before dispatch or transfer.

Questions and answers

Common planning decisions

Short answers to issues that can change preparation, scope, timing or interpretation.

What should I send for Circular Dichroism Spectroscopy?

Provide film / coating, liquid / solution, biological / soft material as applicable. Exact quantity, dimensions and preparation are confirmed during technical review.

Which analysis option should I choose?

Choose the mode around the decision you need to make. For CD or CPL spectrum, start with far-UV, near-UV, or visible CD; add CPL emission when comparison or quantification is required.

How long will the test take?

Typical turnaround is 7 working days after sample acceptance and method confirmation.

What can limit the result?

Scattering, linear dichroism, concentration error, and cell artefacts can mimic weak signals. Structural interpretation is model-dependent.

Configure the service

Send the information needed to scope CD correctly

  • Sample form, material, dimensions and quantity
  • Feature or decision the result must address
  • Required comparison, acceptance criterion or reference
  • Preferred output and reporting depth
CD analysisfrom£75

Typical turnaround: 7 working days

Configure & Book