Enantiomeric ratio
chiral HPLC
Material Analysis · Chromatography & Diagnostics
Enantiomeric Excess Analysis (Chiral ee)
Characterise enantiomeric ratio, enantiomeric excess, and chiral purity and minor-enantiomer content using a scope agreed around your sample and decision.
- Price
- from£120 per sample, excl. VAT
- Turnaround
- 8 working days Preparation and scope dependent
- Available platforms
- Shimadzu Nexera UCWaters ACQUITY UPC2
- Typical outputs
- Chiral chromatogramEnantiomeric ratio and eeSystem-suitability and method conditionsProcessed chromatogram or spectrum
Why this service
What Chiral ee can help you understand
Enantiomeric Excess Analysis is selected when the project needs defensible information on enantiomeric ratio, enantiomeric excess, or chiral purity and minor-enantiomer content. A chiral chromatographic…
Enantiomeric excess
chiral SFC/UPC2
Chiral purity and minor-enantiomer content
derivatisation or chiral GC where appropriate
Choose the scope
Start from the question, not the tool
The method, preparation route and reporting depth depend on what you need to decide.
Chiral HPLC
enantiomeric ratio
- Best used when
- enantiomeric ratio
- Typical result
- Chiral chromatogram
- Preparation note
- Declare volatility, corrosivity, suspended solids and any storage or temperature requirement.
Chiral SFC/UPC2
enantiomeric excess
- Best used when
- enantiomeric excess
- Typical result
- Enantiomeric ratio and ee
- Preparation note
- Declare volatility, corrosivity, suspended solids and any storage or temperature requirement.
Derivatisation or chiral GC where appropriate
chiral purity and minor-enantiomer content
- Best used when
- chiral purity and minor-enantiomer content
- Typical result
- System-suitability and method conditions
- Preparation note
- Declare volatility, corrosivity, suspended solids and any storage or temperature requirement.
Common outputs
A result package matched to the decision you need to make
Fields, conditions, processing and file formats are confirmed before work begins.
Chiral chromatogram reported with the agreed units, sample reference and measurement conditions.
Enantiomeric ratio and ee supplied in a labelled format suitable for direct sample or condition comparison.
System-suitability and method conditions provided with the processing basis and quality checks agreed during technical review.
Processed chromatogram or spectrum included when selected in the confirmed reporting scope.
Sample requirements
What to provide before work begins
Provide representative, clearly labelled samples and identify the decision, feature or comparison that matters.
| Suitable sample | Submission requirement | Planning note |
|---|---|---|
| Liquid / solution | Provide a sealed, compatible container labelled with composition, concentration and solvent. | Declare volatility, corrosivity, suspended solids and any storage or temperature requirement. |
Objective: state the decision, comparison or acceptance criterion the work must support.
Handling and access: declare hazards, instability, confidentiality, file constraints or special logistics before dispatch or transfer.
Questions and answers
Common planning decisions
Short answers to issues that can change preparation, scope, timing or interpretation.
What should I send for Enantiomeric Excess Analysis?
Provide liquid / solution as applicable. Exact quantity, dimensions and preparation are confirmed during technical review.
Which analysis option should I choose?
Choose the mode around the decision you need to make. For enantiomeric ratio, start with chiral HPLC; add chiral SFC/UPC2 when comparison or quantification is required.
How long will the test take?
Typical turnaround is 8 working days after sample acceptance and method confirmation.
What can limit the result?
Column screening may be required and elution order must be established. Peak-area response is assumed equal unless validated otherwise.
Configure the service
Send the information needed to scope Chiral ee correctly
- Sample form, material, dimensions and quantity
- Feature or decision the result must address
- Required comparison, acceptance criterion or reference
- Preferred output and reporting depth